A research paper by the Oxford University Clinical Research Group, published on August 10th in The Lancet, alarmingly revealed that vaccinated individuals carry 251 times the load of Covid-19 viruses in their nostrils compared to the unvaccinated.
Research Paper Details
Transmission of SARS-CoV-2 Delta Variant Among Vaccinated Healthcare Workers, Vietnam
Abstract Background: Data on breakthrough SARS-CoV-2 Delta variant infections are limited. Methods: We studied breakthrough infections among healthcare workers of a major infectious diseases hospital in Vietnam. We collected demographics, vaccination history and results of PCR diagnosis alongside clinical data. We measured SARS-CoV-2 (neutralizing) antibodies at diagnosis, and at week 1, 2 and 3 after diagnosis. We sequenced the viruses using ARTIC protocol. Findings: Between 11th–25th June 2021 (week 7–8 after dose 2), 69 healthcare workers were tested positive for SARS-CoV-2. 62 participated in the clinical study. 49 were (pre)symptomatic with one requiring oxygen supplementation. All recovered uneventfully. 23 complete-genome sequences were obtained. They all belonged to the Delta variant, and were phylogenetically distinct from the contemporary Delta variant sequences obtained from community transmission cases, suggestive of ongoing transmission between the workers. Viral loads of breakthrough Delta variant infection cases were 251 times higher than those of cases infected with old strains detected between March-April 2020. Time from diagnosis to PCR negative was 8–33 days (median: 21). Neutralizing antibody levels after vaccination and at diagnosis of the cases were lower than those in the matched uninfected controls. There was no correlation between vaccine-induced neutralizing antibody levels and viral loads or the development of symptoms. Interpretation: Breakthrough Delta variant infections are associated with high viral loads, prolonged PCR positivity, and low levels of vaccine-induced neutralizing antibodies, explaining the transmission between the vaccinated people. Physical distancing measures remain critical to reduce SARS-CoV-2 Delta variant transmission. Funding: Wellcome (106680/B/14/Z and 204904/Z/16/Z). Declaration of Interest: None to declare. Ethical Approval: The study was approved by the Institutional Review Board of HTD and the Oxford Tropical Research Ethics Committee, University of Oxford, UK.
While moderating the symptoms of infection, the Covid-19 vaccine allows vaccinated individuals to carry unusually high viral loads without initially becoming unwell, potentially transforming them into presymptomatic superspreaders.
This could help explain the dramatic surge of breakthrough cases in fully vaccinated populations around the world.
Chau et al, the paper’s authors, demonstrated widespread vaccine failure and transmission under tightly controlled conditions in a hospital in lockdown in Ho Chi Minh City, Vietnam.
The researchers studied healthcare workers who were unable to leave the hospital for two weeks. Data showed that workers who were fully vaccinated – about two months after receiving the AstraZeneca Covid-19 vaccine – caught, carried and presumably transmitted the Delta variant of the virus to their vaccinated colleagues.
Not only that, it is almost certain that these fully vaccinated individuals also transmitted the Delta variant to susceptible unvaccinated people, including their patients.
Sequencing of strains confirmed that the workers passed SARS-CoV-2 to one another.
These findings are consistent with observations in the US from Farinholt and colleagues, and congruent with comments by the director of the Centers for Disease Control and Prevention (CDC) conceding Covid-19 vaccines have failed to stop transmission.
Despite this, the Covid-19 vaccines have been mandated in countries globally, including the US, and booster shots have been announced as a way to combat the rise in reported infections and the delta variant. Of course, this only confirms that the vaccines are completely ineffective at preventing the spread of the virus and do more harm than good.